Based on the comparative experiment results, the effects of H2O and CO2contaminants on kerosene-fueled supersonic combustion were carefully investigated by numerical approaches and chemical kinetics analysis method, which can provide detailed insight into the vitiation effects on flow field and combustion chemistry that cannot be resolved by experimental instruments available. The two-dimensional reacting flow simulation of kerosene-fueled combustor flowpath was completed. During the present studies, the inflow total temperature, total pressure and oxygen mole fraction at combustor entrance were strictly matched between clean airstream and various vitiated airstream, and the working fuel equivalence ratio was also an important parameter to be strictly matched. The numerical results were compared with experimental data to validate the accuracy of the numerical modeling, and then the kinetics effects of H2O and CO2contaminants and the resulting combustion performance change were analyzed and discussed. The present efforts suggest that:(1) the numerical wall-pressure profiles agree well with the experimental measurement, both of which indicate the same combustor performance in clean air inflow and the same trend of vitiation effects in vitiated air inflow; (2) the presence of H2O or H2O+CO2contaminants results in combustor performance deterioration characterized by the decreases of combustion induced pressure-rise, combustion efficiency and streamwise impulse relative to those in clean air.