初发脑卒中幸存者长期生命质量变化趋势研究

Changes in Health-related Quality of Life in Incipient Stroke Survivors

中文关键词:  脑卒中长期生命质量变化趋势多水平线性模型

英文关键词:StrokeLong-term quality of lifeTrendsMult-level model

中文摘要:

      目的 评价初发脑卒中幸存者的长期生命质量变化趋势。方法 采用简明健康测量量表（SF-12）测量467名首次脑卒中幸存者住院期间以及出院后2年内的生命质量；并采用多水平线性模型比较不同类型患者的生命质量变化趋势是否相同。结果 脑卒中患者住院期间（基线）躯体健康总评分（PCS）为31.50±10.49，精神健康总评分（MCS）为51.92±10.03；随着随访时间的增长PCS与MCS评分都有所增加，但MCS评分在15个月后有轻微下降，女性PCS评分在2年随访期间均低于男性；多水平线性模型分析结果提示不同性别及不同教育程度患者PCS评分随时间变化趋势相同，不同年龄患者PCS评分变化趋势不相同，年龄较大者PCS评分随时间增加速度较慢（\β9=－0.013，\P=0.03）；不同年龄、不同性别、不同教育程度患者之间MCS评分随时间变化趋势相同。 结论 年长者、女性、初中及以下教育程度的脑卒中患者在首次发作后2年内生命质量相对较低，建议给予这类患者更多关注。

英文摘要:

      Objective To assess the long-term changes in quality of life of stroke patients. Methods A total of 467 stroke survivors were recruited for this study. The participants completed the 12-Item Short Form Health Survey (SF-12) at a three-month interval over two years. Multi-level modelling was performed to identify the trend of changes and associated demographic characteristics. Results The participants had (31.50±10.49) PCS and (51.92±10.03) MCS at the baseline survey. Overall, PCS and MCS scores increased over time, but MCS scores declined slightly 15 months later. Men had higher PCS scores than women.The multi-level model revealed similar trends of PCS changes in those with different gender and education.Older patients had slower changes in quality of life over time (\β9=－0.013，\P=0.03) compared with their younger counterparts.The trends of MCS changes were similar among those with different age, gender and education. Conclusion Support should be strengthened for female stroke survivors and those with older age and lower levels of education.